BDBM119877 SL809::US9073941, 502

SMILES COc1ccc(NC(=O)CN(C)S(=O)(=O)c2cc(Br)cnc2N)cc1OC

InChI Key InChIKey=MICNYUJMEYAOJU-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 119877   

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandPNGBDBM119877(SL809 | US9073941, 502)
Affinity DataIC50: 840nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
Go to US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Weill Cornell Medical College

LigandPNGBDBM119877(SL809 | US9073941, 502)
Affinity DataKi:  93nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details Article
PubMed
TargetPrephenate dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Weill Cornell Medical College

LigandPNGBDBM119877(SL809 | US9073941, 502)
Affinity DataKi:  155nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details Article
PubMed