BDBM50241294 CHEMBL240954::SL-0101::kaempferol 3-O-(3'',4''-di-O-acetyl-alpha-L-rhamnopyranoside::kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyranoside)

SMILES C[C@@H]1O[C@@H](Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)cc2)[C@H](O)[C@H](OC(C)=O)[C@H]1OC(C)=O

InChI Key InChIKey=POZDUGKSCAGWQI-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50241294   

TargetRibosomal protein S6 kinase alpha-3(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50241294(kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyra...)
Affinity DataIC50: 370nMAssay Description:Inhibition of RSK2 (unknown origin) assessed as phosphorylation by Western lightning enhanced chemiluminescent reagent/HRP activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Toyama Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50241294(kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyra...)
Affinity DataIC50: 2.06E+4nMAssay Description:Inhibition of human CYP3A4 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Toyama Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50241294(kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyra...)
Affinity DataIC50: 5.05E+4nMAssay Description:Inhibition of human CYP2D6 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50241294(kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyra...)
Affinity DataIC50: 89nMAssay Description:Inhibition of his-tagged active RSK2 (unknown origin) expressed in Sf9 cells after 10 to 45 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50241294(kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyra...)
Affinity DataIC50: 89nMAssay Description:Inhibition of GST-fused RSK2 (unknown origin) after 10 to 45 mins by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50241294(kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyra...)
Affinity DataIC50: 990nMAssay Description:Inhibition of recombinant RSK2 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in substrate phosphorylation using G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50241294(kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyra...)
Affinity DataIC50: 583nMAssay Description:Inhibition of His-tagged RSK2 expressed in Sf9 cells using ERalpha-Ser167 RLASTND as substrate after 120 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50241294(kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyra...)
Affinity DataIC50: 89nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50241294(kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyra...)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of RSK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed