BDBM50001031 3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL330376::SKF 10,047 (+)::SKF 10,047 (-)::SKF 10047

SMILES C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CC=C

InChI Key InChIKey=LGQCVMYAEFTEFN-UHFFFAOYSA-N

Data  35 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 35 hits for monomerid = 50001031   

TargetKappa-type opioid receptor(Rhesus macaque)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]U69,593 from KOR in monkey brain cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rhesus macaque)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]DAMGO from MOR in monkey brain cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Molecular Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  1.15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetOpioid receptor delta 1(Rhesus macaque)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]naltrindole from DOR in monkey brain cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Syntex Discovery Research

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  50.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  75nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  93nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  117nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  134nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  229nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  319nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  343nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  365nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  375nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  405nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  530nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  571nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  625nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  690nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  821nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  895nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  1.35E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  1.44E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  1.86E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Syntex Discovery Research

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  1.91E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  2.85E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi:  4.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Vanderbilt University

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Vanderbilt University

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Vanderbilt University

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Syntex Discovery Research

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Syntex Discovery Research

Curated by PDSP Ki Database
LigandPNGBDBM50001031(SKF 10,047 (-) | CHEMBL330376 | SKF 10,047 (+) | S...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed