BDBM86717 CAS_5218788::CHEMBL88553::NSC_5218788::SIB-1757

SMILES Cc1ccc(O)c(N=Nc2ccccc2)n1

InChI Key InChIKey=LOCPVWIREQIGNQ-UHFFFAOYSA-N

Data  13 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 86717   

TargetMetabotropic glutamate receptor 1(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataIC50: 370nMAssay Description:Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of [3H]MPEP binding to mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataKi:  328nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataKi:  346nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataKi:  357nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataKi:  370nMAssay Description:Agonist potency against cloned metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataKi:  486nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataKi:  1.10E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataKi: >1.00E+5nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataKi: >1.00E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 6 (mGluR-6).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataKi: >1.00E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 7 (mGluR-7).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataKi: >1.00E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 3 (mGluR-3).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataKi: >1.00E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 8 (mGluR-8).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataKi: >1.00E+5nMAssay Description:Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataKi: >1.00E+5nMAssay Description:Antagonist potency against cloned Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed