BDBM642313 (+)-(R)-(5-amino-5-(1-(2-((2- fluorobenzyl)amino)-2-oxoethyl)-1H- tetrazol-5-yl)pentyl)boronic acid::SHK242::US11845767, Example 359

SMILES N[C@H](CCCCB(O)O)c1nnnn1CC(=O)NCc1ccccc1F

InChI Key InChIKey=IAJPFDZFZSDEOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 642313   

TargetArginase-1(Human)
Rijksuniversiteit Groningen

US Patent
LigandPNGBDBM642313((+)-(R)-(5-amino-5-(1-(2-((2- fluorobenzyl)amino)-...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2024
Entry Details
Go to US Patent

TargetArginase-2, mitochondrial(Human)
Rijksuniversiteit Groningen

US Patent
LigandPNGBDBM642313((+)-(R)-(5-amino-5-(1-(2-((2- fluorobenzyl)amino)-...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2024
Entry Details
Go to US Patent