BDBM645035 G**YC+SRSYPPVC+IPD::SFMI-2::US20240010684, Ref. No 8

SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](CCc3ccc(O)cc3)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]3CCCN3C1=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N2

InChI Key InChIKey=RLHCPQYMWLFUIF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 645035   

TargetMannan-binding lectin serine protease 1(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645035(US20240010684, Ref. No 8 | SFMI-2 | G**YC+SRSYPPVC...)
Affinity DataIC50: 8.13E+3nMAssay Description:Recombinant human MASP1 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
Go to US Patent

TargetMannan-binding lectin serine protease 1(Rat)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645035(US20240010684, Ref. No 8 | SFMI-2 | G**YC+SRSYPPVC...)
Affinity DataIC50: 1.00E+3nMAssay Description:Recombinant rat MASP1 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
Go to US Patent

TargetMannan-binding lectin serine protease 2(Rat)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645035(US20240010684, Ref. No 8 | SFMI-2 | G**YC+SRSYPPVC...)
Affinity DataIC50: 126nMAssay Description:Recombinant rat MASP2 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
Go to US Patent