BDBM50601391 CHEMBL2086790::SCH-53870

SMILES ONc1ccc(cc1)S(=O)(=O)NCCOc1ccc2ccccc2c1

InChI Key InChIKey=WPPIAVCIUZNQCQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50601391   

TargetGTPase KRas(Human)
Massachusetts College of Pharmacy and Health Sciences University

Curated by ChEMBL
LigandPNGBDBM50601391(CHEMBL2086790 | SCH-53870)
Affinity DataIC50: 500nMAssay Description:Binding affinity to GDP-bound KRAS G12V RAS mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University

Curated by ChEMBL
LigandPNGBDBM50601391(CHEMBL2086790 | SCH-53870)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of human p21 h-RAS assessed as reduction in C-Cdc25 stimulated nucleotide exchange by luminescence spectrometer based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed