BDBM50289986 4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5-chloro-2-methoxy-benzamide; hydrochloride::CHEMBL558226::SC-52491

SMILES COc1cc(N)c(Cl)cc1C(=O)NC1C2CC3CN(CC13)C2

InChI Key

Data  1 KI  8 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50289986   

TargetAlpha-1B adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289986(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for inhibitory activity against adrenergic alpha-1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289986(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for inhibitory activity against Tachykinin receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289986(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5...)
Affinity DataEC50:  51nMAssay Description:Agonist activity against serotonin 5-HT4 receptor in rat tunica muscularis mucosae assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289986(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for inhibitory activity against Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289986(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was selective with respect to binding at the Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetD(1A) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289986(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for inhibitory activity against Dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289986(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for inhibitory activity against adrenergic alpha-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289986(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for inhibitory activity against Beta adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289986(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for inhibitory activity against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target5-hydroxytryptamine receptor 3A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289986(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5...)
Affinity DataKi:  1.20nMAssay Description:Compound was tested for its binding affinity for the 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article