BDBM706143 SB-FAP-08::US20240382629, Example ix

SMILES [H]c1ccc(OC2=C(/C=C/C3=[N+](CCCCCC(=O)N[C@@H](CCCCn4cc(CCC(=O)NCCCOc5cccc(/C(=CC=N)C(=O)NCC(=O)N6CCCC6C#N)c5)nn4)C(=O)NCCCCCC(=O)N(CCCCC([H])NC(=O)N[C@@H](CCC(=O)O)C(=O)O)Cc4ccc(Br)cc4)c4ccc(C)cc4C3(C)C)CCC/C2=CC=C2N(CCCCS(=O)(=O)O)c3ccc([H])cc3C2(C)C)cc1

InChI Key InChIKey=PCHRROMHSFRTIA-UHFFFAOYSA-O

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 706143   

TargetDipeptidyl peptidase 4(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706143(SB-FAP-08 | US20240382629, Example ix)
Affinity DataIC50: 2.70E+4nMAssay Description:PSMA binding affinities of the compounds were determined using a competitive inhibition assay as previously reported. Banerjee et al., 2011. FAP, pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
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TargetPresequence protease, mitochondrial(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706143(SB-FAP-08 | US20240382629, Example ix)
Affinity DataIC50: 1.76E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706143(SB-FAP-08 | US20240382629, Example ix)
Affinity DataIC50: 4.67nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
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TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706143(SB-FAP-08 | US20240382629, Example ix)
Affinity DataIC50: 23.3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706143(SB-FAP-08 | US20240382629, Example ix)
Affinity DataKi:  0.930nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706143(SB-FAP-08 | US20240382629, Example ix)
Affinity DataKi:  4.66nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent