BDBM706135 SB-FAP-01::US20240382629, Example i

SMILES [H]C(CCCCN(Cc1ccc(Br)cc1)C(=O)CCCCNC(=O)[C@H](CCCCNC(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1)NC(=O)CCOCCOCCOCCn1cc(CCC(=O)NCCCOc2ccc3nccc(C(=O)NCC(=O)N4CCC[C@H]4C#N)c3c2)nn1)NC(=O)N[C@@H](CCC(=O)O)C(=O)O

InChI Key InChIKey=VZMSNDLDHMJHAH-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 706135   

TargetDipeptidyl peptidase 4(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706135(SB-FAP-01 | US20240382629, Example i)
Affinity DataIC50: 1.69E+4nMAssay Description:PSMA binding affinities of the compounds were determined using a competitive inhibition assay as previously reported. Banerjee et al., 2011. FAP, pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
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TargetPresequence protease, mitochondrial(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706135(SB-FAP-01 | US20240382629, Example i)
Affinity DataIC50: 350nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706135(SB-FAP-01 | US20240382629, Example i)
Affinity DataIC50: 1.79nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706135(SB-FAP-01 | US20240382629, Example i)
Affinity DataIC50: 83.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706135(SB-FAP-01 | US20240382629, Example i)
Affinity DataKi:  0.360nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706135(SB-FAP-01 | US20240382629, Example i)
Affinity DataKi:  16.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent