BDBM50053424 4-{3-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-imidazol-1-yl]-propyl}-morpholine::CHEMBL14112::SB-210313

SMILES Fc1ccc(cc1)-c1ncn(CCCN2CCOCC2)c1-c1ccncc1

InChI Key InChIKey=ANWALZPQHPAZFO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50053424   

TargetProstaglandin G/H synthase 1(Sheep)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053424(SB-210313 | 4-{3-[4-(4-Fluoro-phenyl)-5-pyridin-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against Prostaglandin H2 synthase 1 (PGHS-1) from ram seminal vesicleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50053424(SB-210313 | 4-{3-[4-(4-Fluoro-phenyl)-5-pyridin-4-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory concentration against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053424(SB-210313 | 4-{3-[4-(4-Fluoro-phenyl)-5-pyridin-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053424(SB-210313 | 4-{3-[4-(4-Fluoro-phenyl)-5-pyridin-4-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Compound was tested for inhibition of p38 MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed