BDBM50054827 CHEMBL85094::SB-208651::{8-[(4-Carbamimidoyl-phenyl)-methyl-carbamoyl]-3-oxo-4-phenethyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-2-yl}-acetic acid::{8-[(4-Carbamimidoyl-phenyl)-methyl-carbamoyl]-3-oxo-4-phenethyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-2-yl}-acetic acid(SB-208651)

SMILES CN(C(=O)c1ccc2CN(CCc3ccccc3)C(=O)C(CC(O)=O)Nc2c1)c1ccc(cc1)C(N)=N

InChI Key InChIKey=WCZAIWWFRSMLCO-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054827   

TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50054827({8-[(4-Carbamimidoyl-phenyl)-methyl-carbamoyl]-3-o...)
Affinity DataIC50: 65nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50054827({8-[(4-Carbamimidoyl-phenyl)-methyl-carbamoyl]-3-o...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50054827({8-[(4-Carbamimidoyl-phenyl)-methyl-carbamoyl]-3-o...)
Affinity DataKi:  1.60nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]1 binding to purified Fibrinogen Receptor isolated from human p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50054827({8-[(4-Carbamimidoyl-phenyl)-methyl-carbamoyl]-3-o...)
Affinity DataKi:  1.60nMAssay Description:In vitro binding affinity against human alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article