BDBM50421360 CHEMBL358119::SB-207058

SMILES CCCCN1CCC(COC(=O)c2c3OCCCn3c3ccccc23)CC1

InChI Key InChIKey=HATXPTCDDBRERG-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50421360   

Target5-hydroxytryptamine receptor 4(Guinea pig)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50421360(SB-207058 | CHEMBL358119)
Affinity DataIC50: 0.0250nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50421360(SB-207058 | CHEMBL358119)
Affinity DataIC50: 0.0251nMAssay Description:Ability to block 5-HT4 receptor mediated effect of 5-HT was assessed in the guinea-pig distal colon longitudinal muscle myenteric plexus preparation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

LigandPNGBDBM50421360(SB-207058 | CHEMBL358119)
Affinity DataKi:  0.0631nMAssay Description:Compound was evaluated for its ability to inhibit the binding of 5-HT4 receptor radioligand [125I]SB 207710 to piglet hippocampal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article