BDBM20283 2-hydroxy-4-(2-{[(4-methylbenzene)sulfonyl]oxy}acetamido)benzoic acid::NSC 74859::S3I-201::cid_252682
SMILES Cc1ccc(cc1)S(=O)(=O)OCC(=O)Nc1ccc(C(O)=O)c(O)c1
InChI Key InChIKey=HWNUSGNZBAISFM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 20283
TargetSignal transducer and activator of transcription 3(Human)
Moffitt Cancer Center
Curated by ChEMBL
Moffitt Cancer Center
Curated by ChEMBL
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of STAT3 (unknown origin) dimerization by EMSAMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Human)
Moffitt Cancer Center
Curated by ChEMBL
Moffitt Cancer Center
Curated by ChEMBL
TargetSignal transducer and activator of transcription 3(Human)
Moffitt Cancer Center
Curated by ChEMBL
Moffitt Cancer Center
Curated by ChEMBL
TargetSignal transducer and activator of transcription 3(Human)
Moffitt Cancer Center
Curated by ChEMBL
Moffitt Cancer Center
Curated by ChEMBL
TargetSignal transducer and activator of transcription 3(Human)
Moffitt Cancer Center
Curated by ChEMBL
Moffitt Cancer Center
Curated by ChEMBL
TargetSignal transducer and activator of transcription 3(Human)
Moffitt Cancer Center
Curated by ChEMBL
Moffitt Cancer Center
Curated by ChEMBL
TargetSignal transducer and activator of transcription 3(Human)
Moffitt Cancer Center
Curated by ChEMBL
Moffitt Cancer Center
Curated by ChEMBL
TargetSignal transducer and activator of transcription 3(Human)
Moffitt Cancer Center
Curated by ChEMBL
Moffitt Cancer Center
Curated by ChEMBL
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of STAT3 (unknown origin) binding to DNA incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Human)
Moffitt Cancer Center
Curated by ChEMBL
Moffitt Cancer Center
Curated by ChEMBL
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of STAT3 (unknown origin)More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mouse)
University of Central Florida College of Medicine
University of Central Florida College of Medicine
Affinity DataIC50: 8.60E+4nMpH: 7.8 T: 2°CAssay Description:STAT proteins were expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Human)
Moffitt Cancer Center
Curated by ChEMBL
Moffitt Cancer Center
Curated by ChEMBL
Affinity DataIC50: 8.40E+4nMAssay Description:Binding affinity to Stat3 (unknown origin) using hSIE as probe preincubated for 30 mins followed by hSIE addition by electrophoretic mobility shift a...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mouse)
University of Central Florida College of Medicine
University of Central Florida College of Medicine
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of STAT3 dimerization in EGF-stimulated mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction aft...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 1(Mouse)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of STAT1 dimerization in EGF-stimulated mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT1-DNA interaction aft...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mouse)
University of Central Florida College of Medicine
University of Central Florida College of Medicine
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
TargetCarboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1(Human)
Burnham Center For Chemical Genomics
Curated by PubChem BioAssay
Burnham Center For Chemical Genomics
Curated by PubChem BioAssay
Affinity DataIC50: 4.64E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 1-alpha/beta/3(Mouse)
University of Central Florida College of Medicine
University of Central Florida College of Medicine
Affinity DataIC50: 1.60E+5nMpH: 7.8 T: 2°CAssay Description:STAT proteins were expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 1-alpha/beta(Human)
University of Central Florida College of Medicine
University of Central Florida College of Medicine
Affinity DataIC50: 3.00E+5nMpH: 7.8 T: 2°CAssay Description:STAT proteins were expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Human)
Moffitt Cancer Center
Curated by ChEMBL
Moffitt Cancer Center
Curated by ChEMBL
Affinity DataKi: 8.00E+4nMAssay Description:Inhibition of STAT3 SH2 domain assessed as inhibition of STAT3 SH2-phosphotyrosine interaction after 15 mins by fluorescence polarization assayMore data for this Ligand-Target Pair