BDBM2463 (6E)-2-(cyclohexylsulfanyl)-5,5-dimethyl-6-(phenylmethylidene)-3,4,5,6-tetrahydropyrimidin-4-one::S-DABO::thio-DABO 9f

SMILES CC1(C)C(=O)NC(SC2CCCCC2)=N\C1=C\c1ccccc1

InChI Key InChIKey=CMJYILLTYBMZAF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2463   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2463(S-DABO | (6E)-2-(cyclohexylsulfanyl)-5,5-dimethyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2004
Entry Details Article
PubMed