BDBM2458 (6E)-5,5-dimethyl-2-(methylsulfanyl)-6-(phenylmethylidene)-3,4,5,6-tetrahydropyrimidin-4-one::5,5-Dimethyl-2-(methylthio)-oxo-6-(phenylmethenyl)-3,4,5,6-tetrahydropyrimidine::S-DABO::thio-DABO 9-a

SMILES CSC1=N\C(=C\c2ccccc2)C(C)(C)C(=O)N1

InChI Key InChIKey=RIFGLRPLDVBMPO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2458   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2458(S-DABO | 5,5-Dimethyl-2-(methylthio)-oxo-6-(phenyl...)
Affinity DataIC50: 6.10E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2004
Entry Details Article
PubMed