BDBM2451 6-Benzyl-2-(cyclohexylthio)-3,4-dihydro-5-methyl-4-oxopyrimidine::6-benzyl-2-(cyclohexylsulfanyl)-5-methyl-3,4-dihydropyrimidin-4-one::S-DABO::thio-DABO 8f

SMILES Cc1c(Cc2ccccc2)nc(SC2CCCCC2)[nH]c1=O

InChI Key InChIKey=DTCKCBGDRHXTII-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2451   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2451(6-benzyl-2-(cyclohexylsulfanyl)-5-methyl-3,4-dihyd...)
Affinity DataIC50: 4.30E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2004
Entry Details Article
PubMed