BDBM2443 2-(butan-2-ylsulfanyl)-6-[(3-methylphenyl)methyl]-3,4-dihydropyrimidin-4-one::3,4-Dihydro-6-(3-methylbenzyl)-2-(( 1-methylpropyl)thio)-4-oxopyrimidine::S-DABO::thio-DABO 7j

SMILES CCC(C)Sc1nc(Cc2cccc(C)c2)cc(=O)[nH]1

InChI Key InChIKey=OIKHAQDPOAMHAG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2443   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2443(2-(butan-2-ylsulfanyl)-6-[(3-methylphenyl)methyl]-...)
Affinity DataIC50: 1.20E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2004
Entry Details Article
PubMed