BDBM2426 2-(cyclopentylsulfanyl)-5-methyl-6-(naphthalen-1-ylmethyl)-3,4-dihydropyrimidin-4-one::S-DABO::thio-DABO 10k

SMILES Cc1c(Cc2cccc3ccccc23)nc(SC2CCCC2)[nH]c1=O

InChI Key InChIKey=IIALOYSJVJWXRV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2426   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2426(S-DABO | 2-(cyclopentylsulfanyl)-5-methyl-6-(napht...)
Affinity DataIC50: 4.50E+4nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2004
Entry Details Article
PubMed