BDBM50333120 CHEMBL1631581::Rustmicin

SMILES CC[C@@H]1CC(=O)[C@H](C)C(=O)[C@@](O)(CO)C\C(OC)=C\[C@@H](C)CC(=C)\C=C1/C

InChI Key InChIKey=LCMZUWGOWDQRBC-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50333120   

LigandPNGBDBM50333120(Rustmicin | CHEMBL1631581)
Affinity DataIC50: 2.72E+4nMAssay Description:Inhibition of aureobasidin A-resistant Saccharomyces cerevisiae inositol phosphorylceramide synthase preincubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetInositol phosphorylceramide synthase(Yeast)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50333120(Rustmicin | CHEMBL1631581)
Affinity DataIC50: 3.80nMAssay Description:Reversible inhibition of Candida albicans inositol phosphorylceramide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
LigandPNGBDBM50333120(Rustmicin | CHEMBL1631581)
Affinity DataIC50: 3.80nMAssay Description:Reversible inhibition of Saccharomyces cerevisiae inositol phosphorylceramide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
LigandPNGBDBM50333120(Rustmicin | CHEMBL1631581)
Affinity DataIC50: 13nMAssay Description:Inhibition of Saccharomyces cerevisiae SJ21R inositol phosphorylceramide synthase preincubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetInositol phosphorylceramide synthase(Yeast)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50333120(Rustmicin | CHEMBL1631581)
Affinity DataKi:  16nMAssay Description:Inhibition of Candida albicans ATCC 38247 inositol phosphorylceramide synthase preincubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed