BDBM50015985 3-Ethyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione::CHEMBL289116::Rogletimide

SMILES CCC1(CCC(=O)NC1=O)c1ccncc1

InChI Key InChIKey=QXKJWHWUDVQATH-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50015985   

TargetAromatase(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015985(CHEMBL289116 | 3-Ethyl-4,5-dihydro-3H-[3,4']bipyri...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015985(CHEMBL289116 | 3-Ethyl-4,5-dihydro-3H-[3,4']bipyri...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015985(CHEMBL289116 | 3-Ethyl-4,5-dihydro-3H-[3,4']bipyri...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with androstenedioneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015985(CHEMBL289116 | 3-Ethyl-4,5-dihydro-3H-[3,4']bipyri...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibitory constant (Ki) for Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetAromatase(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015985(CHEMBL289116 | 3-Ethyl-4,5-dihydro-3H-[3,4']bipyri...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with testosteroneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015985(CHEMBL289116 | 3-Ethyl-4,5-dihydro-3H-[3,4']bipyri...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with androstenedioneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed