BDBM50330345 CHEMBL1276275::N-(2-(7-(((3R,4R)-4-(4-(3-(2-methoxybenzyloxy)propoxy)phenyl)piperidin-3-yloxy)methyl)-3,4-dihydroquinolin-1(2H)-yl)ethyl)acetamide::Ro-66-1168

SMILES COc1ccccc1COCCCOc1ccc(cc1)[C@H]1CCNC[C@@H]1OCc1ccc2CCCN(CCNC(C)=O)c2c1

InChI Key InChIKey=YKAHCPSTICMMFK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50330345   

TargetRenin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330345(N-(2-(7-(((3R,4R)-4-(4-(3-(2-methoxybenzyloxy)prop...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330345(N-(2-(7-(((3R,4R)-4-(4-(3-(2-methoxybenzyloxy)prop...)
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of human recombinant renin in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330345(N-(2-(7-(((3R,4R)-4-(4-(3-(2-methoxybenzyloxy)prop...)
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of human recombinant rennin in buffer assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed