BDBM50609697 GDC-0134::Gdc-0134::Rg-6000

SMILES Nc1ncc(cc1OC(F)F)-c1cc(nc(n1)N1CCC(F)(F)C1)N1C[C@@H]2C[C@H]1CO2

InChI Key InChIKey=SKMKJBYBPYBDMN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50609697   

TargetProtein delta homolog 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50609697(Gdc-0134 | Rg-6000 | GDC-0134)
Affinity DataIC50: 11nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 12(Human)
Denali Therapeutics

Curated by ChEMBL
LigandPNGBDBM50609697(Gdc-0134 | Rg-6000 | GDC-0134)
Affinity DataIC50: 11nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 13(Human)
Denali Therapeutics

Curated by ChEMBL
LigandPNGBDBM50609697(Gdc-0134 | Rg-6000 | GDC-0134)
Affinity DataIC50: 14nMAssay Description:Inhibition of LZK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed