BDBM50553255 All-Trans-Retinal::CHEBI:17898::Retinal

SMILES CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C=O)/C)/C

InChI Key InChIKey=NCYCYZXNIZJOKI-UHFFFAOYSA-N

Data  2 IC50  1 EC50

PDB links: 480 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50553255   

TargetAlpha-synuclein(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50553255(CHEBI:17898 | All-Trans-Retinal | Retinal)
Affinity DataIC50: 190nMAssay Description:Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50553255(CHEBI:17898 | All-Trans-Retinal | Retinal)
Affinity DataIC50: 180nMAssay Description:Inhibition of amyloid beta (1 to 40) (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50553255(CHEBI:17898 | All-Trans-Retinal | Retinal)
Affinity DataEC50:  200nMAssay Description:Inverse agonist activity at TLX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed