BDBM50212465 Renzapride

SMILES COc1cc(N)c(Cl)cc1C(=O)NC1CCN2CCC1C2

InChI Key InChIKey=DTTGUKXBOVDIES-UHFFFAOYSA-N

Data  10 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50212465   

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50212465(Renzapride)
Affinity DataEC50:  63nMAssay Description:Tested for its agonist potency against the 5-hydroxytryptamine 4 receptor located in the rat esophageal tunica muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50212465(Renzapride)
Affinity DataEC50:  98nMAssay Description:Compound was evaluated for the agonistic activity towards 5-hydroxytryptamine 4 receptor using the rat tunica muscularis mucosae (TMM) esophagus stri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

LigandPNGBDBM50212465(Renzapride)
Affinity DataKi:  5nMAssay Description:Tested for its binding affinity by measuring its ability to displace [3H]granisetron from 5-hydroxytryptamine 3 receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

Target5-hydroxytryptamine receptor 3A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50212465(Renzapride)
Affinity DataKi:  5.60nMAssay Description:Compound was evaluated in vivo for the antagonistic activity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(1A) dopamine receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50212465(Renzapride)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]-SCH- 23390 binding to Dopamine receptor D1 in rat striataMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50212465(Renzapride)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]5-HT binding to 5-hydroxytryptamine 1 receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50212465(Renzapride)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor in rat brain corticesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50212465(Renzapride)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50212465(Renzapride)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]domperidone binding to dopamine receptor D2 in rat striataMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50212465(Renzapride)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]dihydroalprenolol prenolol binding to Beta adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50212465(Renzapride)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]rauwolscine binding to alpha-2 adrenergic receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50212465(Renzapride)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed