BDBM50064455 4-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzyl}-isoxazolidine-3,5-dione::4-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzyl}-isoxazolidine-3,5-dione(JTT-501)::CHEMBL293526::Reglitazar

SMILES Cc1oc(nc1CCOc1ccc(Cc2c(O)[nH]oc2=O)cc1)-c1ccccc1

InChI Key InChIKey=CHFZGXPBBPFZDR-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50064455   

TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM50064455(4-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-be...)
Affinity DataEC50:  4.30E+3nMAssay Description:Agonist activity for murine PPAR alpha receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM50064455(4-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-be...)
Affinity DataEC50:  83nMAssay Description:Agonist activity for Human PPAR gamma receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Mouse)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM50064455(4-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-be...)
Affinity DataEC50:  89nMAssay Description:Agonist activity for murine PPAR gamma receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM50064455(4-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-be...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity for Human PPAR alpha receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM50064455(4-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-be...)
Affinity DataEC50:  1.90E+3nMAssay Description:In vitro transcription activation on human peroxisome proliferator activated receptor-alpha (PPAR alpha)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM50064455(4-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-be...)
Affinity DataEC50:  83nMAssay Description:In vitro transcription activation on human peroxisome proliferator activated receptor-gamma (PPAR gamma)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed