BDBM50033125 3-(4-Chloro-phenyl)-8-methyl-2-(5-phenyl-oxazol-2-yl)-8-aza-bicyclo[3.2.1]octane::CHEMBL117735::RTI-189

SMILES CN1C2CCC1C(C(C2)c1ccc(Cl)cc1)c1ncc(o1)-c1ccccc1

InChI Key InChIKey=ORVMQQOZCWAYLJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033125   

TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50033125(RTI-189 | 3-(4-Chloro-phenyl)-8-methyl-2-(5-phenyl...)
Affinity DataIC50: 1.12E+3nMAssay Description:Binding affinity towards Serotonin transporter was determined using 5-HT [3H]paroxetine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50033125(RTI-189 | 3-(4-Chloro-phenyl)-8-methyl-2-(5-phenyl...)
Affinity DataIC50: 496nMAssay Description:Binding affinity towards Norepinephrine transporter was determined using NE[3H]Nisoxetine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50033125(RTI-189 | 3-(4-Chloro-phenyl)-8-methyl-2-(5-phenyl...)
Affinity DataIC50: 20nMAssay Description:Binding affinity towards dopamine transporter was determined using DA[3H]WIN-35428 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed