BDBM50287379 4-[(S)-2-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pentanoylamino)-4-methyl-pentanoylamino]-benzoic acid methyl ester::CHEMBL288896::RS-39066

SMILES COC(=O)c1ccc(NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)CC(=O)NO)cc1

InChI Key InChIKey=CEEASCNCHQSPKF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287379   

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287379(RS-39066 | 4-[(S)-2-((R)-2-Hydroxycarbamoylmethyl-...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287379(RS-39066 | 4-[(S)-2-((R)-2-Hydroxycarbamoylmethyl-...)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287379(RS-39066 | 4-[(S)-2-((R)-2-Hydroxycarbamoylmethyl-...)
Affinity DataIC50: 0.230nMAssay Description:Inhibition of matrilysin, matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article