BDBM231694 1-Amin-5-Naphthol-7-Sulfonic acid::NCI2602::RR535

SMILES Nc1cccc2c(O)cc(cc12)S(O)(=O)=O

InChI Key InChIKey=GGZZISOUXJHYOY-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 231694   

TargetDual specificity protein phosphatase 5(Human)
Concordia University of Wisconsin

LigandPNGBDBM231694(1-Amin-5-Naphthol-7-Sulfonic acid | RR535 | NCI260...)
Affinity DataIC50: 7.85E+4nMpH: 7.5 T: 2°CAssay Description:Briefly, assays without and with inhibitors were performed in Greiner 96-well clear bottom plates with a total assay volume of 200 μL. The assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 5(Human)
Concordia University of Wisconsin

LigandPNGBDBM231694(1-Amin-5-Naphthol-7-Sulfonic acid | RR535 | NCI260...)
Affinity DataIC50: 1.70E+3nMAssay Description:This assay was done with full-length protein (containing both domains), and using pERK as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 5(Human)
Concordia University of Wisconsin

LigandPNGBDBM231694(1-Amin-5-Naphthol-7-Sulfonic acid | RR535 | NCI260...)
Affinity DataIC50: 5.88E+5nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 5(Human)
Concordia University of Wisconsin

LigandPNGBDBM231694(1-Amin-5-Naphthol-7-Sulfonic acid | RR535 | NCI260...)
Affinity DataIC50: 2.21E+5nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 5(Human)
Concordia University of Wisconsin

LigandPNGBDBM231694(1-Amin-5-Naphthol-7-Sulfonic acid | RR535 | NCI260...)
Affinity DataIC50: 7.25E+5nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 5(Human)
Concordia University of Wisconsin

LigandPNGBDBM231694(1-Amin-5-Naphthol-7-Sulfonic acid | RR535 | NCI260...)
Affinity DataIC50: 3.60E+5nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 5(Human)
Concordia University of Wisconsin

LigandPNGBDBM231694(1-Amin-5-Naphthol-7-Sulfonic acid | RR535 | NCI260...)
Affinity DataIC50: 3.10E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 5(Human)
Concordia University of Wisconsin

LigandPNGBDBM231694(1-Amin-5-Naphthol-7-Sulfonic acid | RR535 | NCI260...)
Affinity DataIC50: 7.88E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 5(Human)
Concordia University of Wisconsin

LigandPNGBDBM231694(1-Amin-5-Naphthol-7-Sulfonic acid | RR535 | NCI260...)
Affinity DataIC50: 3.25E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 5(Human)
Concordia University of Wisconsin

LigandPNGBDBM231694(1-Amin-5-Naphthol-7-Sulfonic acid | RR535 | NCI260...)
Affinity DataIC50: 8.66E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 5(Human)
Concordia University of Wisconsin

LigandPNGBDBM231694(1-Amin-5-Naphthol-7-Sulfonic acid | RR535 | NCI260...)
Affinity DataIC50: 5.90E+3nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 5(Human)
Concordia University of Wisconsin

LigandPNGBDBM231694(1-Amin-5-Naphthol-7-Sulfonic acid | RR535 | NCI260...)
Affinity DataIC50: 1.65E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 5(Human)
Concordia University of Wisconsin

LigandPNGBDBM231694(1-Amin-5-Naphthol-7-Sulfonic acid | RR535 | NCI260...)
Affinity DataIC50: 3.30E+3nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 5(Human)
Concordia University of Wisconsin

LigandPNGBDBM231694(1-Amin-5-Naphthol-7-Sulfonic acid | RR535 | NCI260...)
Affinity DataIC50: 6.30E+3nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 5(Human)
Concordia University of Wisconsin

LigandPNGBDBM231694(1-Amin-5-Naphthol-7-Sulfonic acid | RR535 | NCI260...)
Affinity DataIC50: 2.28E+4nMAssay Description:This assay was done with full-length protein (containing both domains), and using pERK as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed