BDBM50473624 CHEMBL71792::RPR-235316

SMILES COCCCNc1nccc(n1)-c1[nH]c(nc1-c1ccc(F)cc1)[C@H]1OC[C@](C)(CO1)C(=O)NCCOC

InChI Key InChIKey=JYAWNXPPACKSCL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50473624   

TargetMitogen-activated protein kinase 11/12/13/14(Human)
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50473624(RPR-235316 | CHEMBL71792)
Affinity DataIC50: 71nMAssay Description:Inhibition of p38-related TNF alpha release by human monocyte cell line (THP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50473624(RPR-235316 | CHEMBL71792)
Affinity DataIC50: 127nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed