BDBM50006819 2-(4-Benzyloxy-phenyl)-N-hydroxy-N-phenethyl-acetamide::CHEMBL52748::RG-6820

SMILES ON(CCc1ccccc1)C(=O)Cc1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=CCBFWYRWDWBCOM-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50006819   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50006819(RG-6820 | CHEMBL52748 | 2-(4-Benzyloxy-phenyl)-N-h...)
Affinity DataIC50: 320nMAssay Description:In vitro inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rat)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50006819(RG-6820 | CHEMBL52748 | 2-(4-Benzyloxy-phenyl)-N-h...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of rat platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006819(RG-6820 | CHEMBL52748 | 2-(4-Benzyloxy-phenyl)-N-h...)
Affinity DataIC50: 350nMAssay Description:The compound was tested for inhibitory activity against 5-Lipoxygenase in human polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006819(RG-6820 | CHEMBL52748 | 2-(4-Benzyloxy-phenyl)-N-h...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenase using guinea pig supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006819(RG-6820 | CHEMBL52748 | 2-(4-Benzyloxy-phenyl)-N-h...)
Affinity DataIC50: 350nMAssay Description:In vitro inhibition of polymorphonuclear leukocyte derived human 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006819(RG-6820 | CHEMBL52748 | 2-(4-Benzyloxy-phenyl)-N-h...)
Affinity DataKi:  100nMAssay Description:In vitro inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenase in human cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rat)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50006819(RG-6820 | CHEMBL52748 | 2-(4-Benzyloxy-phenyl)-N-h...)
Affinity DataKi:  1.60E+3nMAssay Description:In vitro inhibitory activity against rat platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed