BDBM50347503 RADICICOL

SMILES C[C@@H]1C[C@@H]2O[C@@H]2C=CC=CC(=O)Cc2c(Cl)c(O)cc(O)c2C(=O)O1

InChI Key InChIKey=WYZWZEOGROVVHK-UHFFFAOYSA-N

Data  6 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50347503   

LigandPNGBDBM50347503(RADICICOL)
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of PDHK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50347503(RADICICOL)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of PDHK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50347503(RADICICOL)
Affinity DataIC50: 16nMAssay Description:Binding affinity to Hsp90alpha N-terminal ATPase domain by TR-FRET assay based competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50347503(RADICICOL)
Affinity DataIC50: 530nMAssay Description:Inhibition of Hsp90alpha ATPase activity by malachite green ATP-ase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50347503(RADICICOL)
Affinity DataKd:  2.70nMAssay Description:The compound was tested for binding affinity against isolated N-domain of Heat shock protein HSP 90More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50347503(RADICICOL)
Affinity DataKd:  19nMAssay Description:The compound was tested for binding affinity against yeast Heat shock protein HSP 90More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50347503(RADICICOL)
Affinity DataKd:  4.20nMAssay Description:Binding affinity to recombinant Hsp90 alpha (unknown origin) by surface plasmon resonanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50347503(RADICICOL)
Affinity DataIC50: 27nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50347503(RADICICOL)
Affinity DataKd:  19nMAssay Description:Binding affinity to N-terminal ATP/ADP-binding domain of yeast Hsp90More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50347503(RADICICOL)
Affinity DataIC50: 20nMAssay Description:Inhibition of Hsp90More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed