BDBM50503422 Loreclezole::R 72063

SMILES Cl\C(=C/n1cncn1)c1ccc(Cl)cc1Cl

InChI Key InChIKey=XGLHZTBDUXXHOM-UHFFFAOYSA-N

Data  2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503422   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Vienna

Curated by ChEMBL

LigandBDBM50503422(Loreclezole | R 72063)Copy SMILESCopy InChI

Affinity DataEC50:  1.10E+4nMAssay Description:Positive allosteric modulation of GABA-A alpha1beta3gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as increase in GAB...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
PC cidPC sidSimilars

In Depth
Date in BDB:
2/18/2021
Entry Details Article
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TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Vienna

Curated by ChEMBL

LigandBDBM50503422(Loreclezole | R 72063)Copy SMILESCopy InChI

Affinity DataEC50:  3.80E+4nMAssay Description:Modulation of rat alpha6beta3gamma2 GABA A receptor expressed in Xenopus oocytes assessed as reduction in desensitization at -80 mV holding potential...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
PC cidPC sidSimilars

In Depth
Date in BDB:
4/21/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL