BDBM50014888 4-Benzoylamino-4-dipropylcarbamoyl-butyric acid::CHEMBL316561::Proglumide

SMILES CCCN(CCC)C(=O)C(CCC(O)=O)NC(=O)c1ccccc1

InChI Key InChIKey=DGMKFQYCZXERLX-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50014888   

TargetCholecystokinin receptor type A(Guinea pig)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014888(CHEMBL316561 | 4-Benzoylamino-4-dipropylcarbamoyl-...)
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of binding of [125I]- CCK-33 to guinea pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50014888(CHEMBL316561 | 4-Benzoylamino-4-dipropylcarbamoyl-...)
Affinity DataIC50: 2.50E+6nMAssay Description:In vitro inhibitory activity for binding of [125I](Nle11)-HG-13 to gastrin receptor on isolated rabbit gastric mucosal cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50014888(CHEMBL316561 | 4-Benzoylamino-4-dipropylcarbamoyl-...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibitory activity against binding of [125I](Nle11)-HG-13 to Histamine H2 receptor in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014888(CHEMBL316561 | 4-Benzoylamino-4-dipropylcarbamoyl-...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of binding of [125I]- CCK-33 to rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50014888(CHEMBL316561 | 4-Benzoylamino-4-dipropylcarbamoyl-...)
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibition of binding of [125I]gastrin to Cholecystokinin type B receptor from guinea pig gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetCholecystokinin(Rat)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50014888(CHEMBL316561 | 4-Benzoylamino-4-dipropylcarbamoyl-...)
Affinity DataIC50: 6.00E+5nMAssay Description:Antagonist activity at 125I-labeled CCK-33 in rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholecystokinin(Rat)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50014888(CHEMBL316561 | 4-Benzoylamino-4-dipropylcarbamoyl-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2011
Entry Details Article
PubMed