BDBM50124417 1Alpha,25-Dihydroxy-22-Oxavitamin D3::22-Oxacalcitrol::Maxacalcitol::Prezios::SCH-209579

SMILES C[C@@H]([C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](C[C@@H](C3=C)O)O)C)OCCC(C)(C)O

InChI Key InChIKey=DTXXSJZBSTYZKE-UHFFFAOYSA-N

Data  5 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50124417   

TargetVitamin D3 receptor(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50124417(1Alpha,25-Dihydroxy-22-Oxavitamin D3 | 22-Oxacalci...)
Affinity DataEC50:  38nMAssay Description:Transactivation of VDR in human HaCaT cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50124417(1Alpha,25-Dihydroxy-22-Oxavitamin D3 | 22-Oxacalci...)
Affinity DataEC50:  41nMAssay Description:Transactivation of VDR in human Caco2 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50124417(1Alpha,25-Dihydroxy-22-Oxavitamin D3 | 22-Oxacalci...)
Affinity DataEC50:  0.855nMAssay Description:Activation of VDR in human Jurkat cells expressing lentiviral VDRE-luciferase vector assessed as VDRE-mediated transcriptional activity measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2017
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50124417(1Alpha,25-Dihydroxy-22-Oxavitamin D3 | 22-Oxacalci...)
Affinity DataEC50:  145nMAssay Description:Activation of VDR in human Caco2 cells expressing lentiviral VDRE-luciferase vector assessed as VDRE-mediated transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2017
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50124417(1Alpha,25-Dihydroxy-22-Oxavitamin D3 | 22-Oxacalci...)
Affinity DataEC50:  160nMAssay Description:Activation of VDR in human HaCaT cells expressing lentiviral VDRE-luciferase vector assessed as VDRE-mediated transcriptional activity measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2017
Entry Details Article
PubMed