BDBM53403 (3R,3aR,7aR)-2-benzyl-3-(5-bromo-2-methoxy-phenyl)-7a-methyl-3,3a,6,7-tetrahydroisoindol-1-one::(3R,3aR,7aR)-2-benzyl-3-(5-bromo-2-methoxyphenyl)-7a-methyl-3,3a,6,7-tetrahydroisoindol-1-one::(3R,3aR,7aR)-3-(5-bromanyl-2-methoxy-phenyl)-7a-methyl-2-(phenylmethyl)-3,3a,6,7-tetrahydroisoindol-1-one::(3R,3aR,7aR)-3-(5-bromo-2-methoxyphenyl)-7a-methyl-2-(phenylmethyl)-3,3a,6,7-tetrahydroisoindol-1-one::MLS000882796::PiC::SMR000465410::cid_16060470

SMILES COc1ccc(Br)cc1[C@H]1[C@@H]2C=CCC[C@@]2(C)C(=O)N1Cc1ccccc1

InChI Key InChIKey=KNRYFEGKCSWVBJ-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 53403   

TargetPeptidyl-prolyl cis-trans isomerase ESS1(Baker's yeast)
Tohoku University

LigandPNGBDBM53403((3R,3aR,7aR)-2-benzyl-3-(5-bromo-2-methoxy-phenyl)...)
Affinity DataIC50: 5.00E+3nMpH: 7.0 T: 2°CAssay Description:Assay was carried out measuring the MCA fluorescence using Suc-Ala-Glu-Pro-Phe-MCA as substrate purchased from Japan Peptide Institute Co.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2011
Entry Details Article
PubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53403((3R,3aR,7aR)-2-benzyl-3-(5-bromo-2-methoxy-phenyl)...)
Affinity DataEC50:  3.76E+4nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay
TargetMitochondrial import inner membrane translocase subunit TIM10(Baker's yeast)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM53403((3R,3aR,7aR)-2-benzyl-3-(5-bromo-2-methoxy-phenyl)...)
Affinity DataIC50: 1.21E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetMitochondrial import inner membrane translocase subunit TIM23(Baker's yeast)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM53403((3R,3aR,7aR)-2-benzyl-3-(5-bromo-2-methoxy-phenyl)...)
Affinity DataIC50: 1.43E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2011
Entry Details
PCBioAssay