BDBM50666794 Pf-07054894

SMILES Cc1cn(nc1[C@@H](C2(CCCC2)C)NC3=C(C(=O)C3=O)Nc4ccnc(c4O)C(=O)N(C)C)C

InChI Key InChIKey=WZBSYWCLIMRAHO-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50666794   

TargetC-C chemokine receptor type 6(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666794BDBM50666794(Pf-07054894)
Affinity DataKi:  3.10nMAssay Description:Binding affinity to CCR6 (unknown origin) extracted from HEK293T cell membrane harbouring CCR6_Nluc assessed as inhibition constant incubated for 90 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetC-C chemokine receptor type 6(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666794BDBM50666794(Pf-07054894)
Affinity DataIC50: 5.70nMAssay Description:Antagonist activity at human CCR6 expressed in CHO-K1 cells incubated for 4 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetC-C chemokine receptor type 7(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666794BDBM50666794(Pf-07054894)
Affinity DataKi:  81nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed