BDBM50368315 PROSTRATIN

SMILES C[C@@H]1C[C@@]2([C@@H](C2(C)C)[C@H]3[C@]1([C@@H]4C=C(C(=O)[C@]4(CC(=C3)CO)O)C)O)OC(=O)C

InChI Key InChIKey=BOJKFRKNLSCGHY-UHFFFAOYSA-N

Data  4 KI  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50368315   

LigandPNGBDBM50368315(PROSTRATIN)
Affinity DataEC50:  910nMAssay Description:Activation of PKC in human platelet assessed as induction of platelet aggregation measured within 15 mins by tribidimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50368315(PROSTRATIN)
Affinity DataKi:  4.80nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
S£O Paulo State University (Unesp)

Curated by ChEMBL
LigandPNGBDBM50368315(PROSTRATIN)
Affinity DataKi:  22nMAssay Description:Displacement of 3H-PDBu from recombinant human PKCgamma incubated for 25 mins by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
LigandPNGBDBM50368315(PROSTRATIN)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]PDBu binding to Protein kinase C of CEM cells with 10% fetal calf serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2019
Entry Details Article
PubMed
LigandPNGBDBM50368315(PROSTRATIN)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]PDBu from Protein kinase C of CEM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2019
Entry Details Article
PubMed