BDBM442822 PR-619

SMILES Nc1nc(N)c(SC#N)cc1SC#N

InChI Key InChIKey=ZXOBLNBVNROVLC-UHFFFAOYSA-N

Data  2 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 442822   

TargetReplicase polyprotein 1ab(2019-nCoV)
Fraunhofer Institute For Translational Medicine and Pharmacology (Itmp) and Fraunhofer Cluster of Excellence For Immune Mediated Diseases (Cimd

LigandPNGBDBM442822(PR-619)
Affinity DataIC50: 410nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details Article

TargetReplicase polyprotein 1ab(2019-nCoV)
Fraunhofer Institute For Translational Medicine and Pharmacology (Itmp) and Fraunhofer Cluster of Excellence For Immune Mediated Diseases (Cimd

LigandPNGBDBM442822(PR-619)
Affinity DataIC50: 4.41E+3nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details Article

TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM442822(PR-619)
Affinity DataEC50:  7.20E+3nMAssay Description:Inhibition of USP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 4(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM442822(PR-619)
Affinity DataEC50:  3.90E+3nMAssay Description:Inhibition of USP4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 5(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM442822(PR-619)
Affinity DataEC50:  8.60E+3nMAssay Description:Inhibition of USP5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM442822(PR-619)
Affinity DataEC50:  6.90E+3nMAssay Description:Inhibition of USP7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM442822(PR-619)
Affinity DataEC50:  4.90E+3nMAssay Description:Inhibition of USP8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed