BDBM23841 2-(2-hexylphenyl)-2,3-dihydro-1H-isoindole-1,3-dione::CHEMBL245943::PP60

SMILES CCCCCCc1ccccc1N1C(=O)c2ccccc2C1=O

InChI Key InChIKey=USXHUJLIZBGCGH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 23841   

TargetAlpha-glucosidase MAL32(Baker's yeast)
University of Tokyo

LigandPNGBDBM23841(CHEMBL245943 | 2-(2-hexylphenyl)-2,3-dihydro-1H-is...)
Affinity DataIC50: 2.47E+4nMpH: 7.0 T: 2°CAssay Description:The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
University of Tokyo

LigandPNGBDBM23841(CHEMBL245943 | 2-(2-hexylphenyl)-2,3-dihydro-1H-is...)
Affinity DataIC50: 1.30E+4nMT: 2°CAssay Description:Human embryonic kidney (HEK) 293 cells were cultured in D-MEM medium. Transfections were performed by the calcium phosphate coprecipitation method. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
University of Tokyo

LigandPNGBDBM23841(CHEMBL245943 | 2-(2-hexylphenyl)-2,3-dihydro-1H-is...)
Affinity DataIC50: 6.50E+4nMAssay Description:The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
University of Tokyo

LigandPNGBDBM23841(CHEMBL245943 | 2-(2-hexylphenyl)-2,3-dihydro-1H-is...)
Affinity DataIC50: 6.50E+4nMAssay Description:Antagonist activity at human recombinant LXRbeta expressed in HEK293 cells assessed as inhibition of T0901317-induced transcriptional activation by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
University of Tokyo

LigandPNGBDBM23841(CHEMBL245943 | 2-(2-hexylphenyl)-2,3-dihydro-1H-is...)
Affinity DataIC50: 1.30E+4nMAssay Description:Antagonist activity at human recombinant LXRalpha expressed in HEK293 cells assessed as inhibition of T0901317-induced transcriptional activation by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed