BDBM50172517 4-Hydroxy-6-(3-hydroxy-propyl)-quinoline-3-carboxylic acid 4-chloro-benzylamide::CHEMBL363625::N-(4-chlorobenzyl)-4-hydroxy-6-(3-hydroxypropyl)quinoline-3-carboxamide::PNU-181465

SMILES OCCCc1ccc2ncc(C(=O)NCc3ccc(Cl)cc3)c(O)c2c1

InChI Key InChIKey=VMPDJKLCDOCUMM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50172517   

TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172517(PNU-181465 | N-(4-chlorobenzyl)-4-hydroxy-6-(3-hyd...)
Affinity DataIC50: 400nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172517(PNU-181465 | N-(4-chlorobenzyl)-4-hydroxy-6-(3-hyd...)
Affinity DataIC50: 4.00E+4nMpH: 7.5Assay Description:Inhibition of human alpha DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-1)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172517(PNU-181465 | N-(4-chlorobenzyl)-4-hydroxy-6-(3-hyd...)
Affinity DataIC50: 300nMpH: 7.5Assay Description:Inhibition of herpes simplex virus type 1 DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase delta catalytic subunit(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172517(PNU-181465 | N-(4-chlorobenzyl)-4-hydroxy-6-(3-hyd...)
Affinity DataIC50: 4.00E+4nMpH: 7.5Assay Description:Inhibition of human delta DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-3)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172517(PNU-181465 | N-(4-chlorobenzyl)-4-hydroxy-6-(3-hyd...)
Affinity DataIC50: 4.00E+4nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-3)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172517(PNU-181465 | N-(4-chlorobenzyl)-4-hydroxy-6-(3-hyd...)
Affinity DataIC50: 70nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed