BDBM50171289 Benzenemethanesulfonyl fluoride::CHEMBL190503::PMSF::Phenylmethanesulfonyl fluoride::alpha-toluenesulfonyl fluoride::alpha-toluenesulphonyl fluoride::phenylmethylsulfonyl fluoride

SMILES c1ccc(cc1)CS(=O)(=O)F

InChI Key InChIKey=YBYRMVIVWMBXKQ-UHFFFAOYSA-N

Data  1 KI  7 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50171289   

TargetMyeloblastin(Human)
University of Bergen

Curated by ChEMBL
LigandPNGBDBM50171289(Benzenemethanesulfonyl fluoride | PMSF | Phenylmet...)
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of human PR3 using D-DY-FRET as substrate after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Chang Gung University

Curated by ChEMBL
LigandPNGBDBM50171289(Benzenemethanesulfonyl fluoride | PMSF | Phenylmet...)
Affinity DataIC50: 9.52E+4nMAssay Description:Inhibition of human neutrophil elastase after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Chang Gung University

Curated by ChEMBL
LigandPNGBDBM50171289(Benzenemethanesulfonyl fluoride | PMSF | Phenylmet...)
Affinity DataIC50: 5.22E+4nMAssay Description:Inhibition of human leukocyte elastase after 2 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50171289(Benzenemethanesulfonyl fluoride | PMSF | Phenylmet...)
Affinity DataIC50: 1.30E+4nMAssay Description:Irreversible inhibition of fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50171289(Benzenemethanesulfonyl fluoride | PMSF | Phenylmet...)
Affinity DataIC50: 833nMAssay Description:Inhibition of rat histidine tagged FAAH expressed in Escherichia coli by coumarin ester substrate fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTrypsin(Human)TBA
LigandPNGBDBM50171289(Benzenemethanesulfonyl fluoride | PMSF | Phenylmet...)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of trypsin (unknown origin) using BApNA as substrate incubated for 15 min prior to substrate addition measured after 30 min by UV/VIS spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetChymotrypsinogen A(Bovine)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50171289(Benzenemethanesulfonyl fluoride | PMSF | Phenylmet...)
Affinity DataIC50: 420nMAssay Description:Inhibition of bovine pancreatic alpha chymotrypsin using N-succinyl-Gly-Gly-Phe-p-nitroanilide as substrate preincubated with enzyme for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetTrypsin(Human)TBA
LigandPNGBDBM50171289(Benzenemethanesulfonyl fluoride | PMSF | Phenylmet...)
Affinity DataKi:  1.00E+4nMAssay Description:Competitive inhibition of trypsin (unknown origin) using N-succinyl-phenylalanine-p-nitroanilide as substrate incubated for 20 mins prior to substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article