BDBM50012827 10H-Phenoxazine::CHEMBL276850::PHENOXAZINE

SMILES N1c2ccccc2Oc2ccccc12

InChI Key InChIKey=TZMSYXZUNZXBOL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50012827   

LigandPNGBDBM50012827(10H-Phenoxazine | CHEMBL276850 | PHENOXAZINE)
Affinity DataIC50: 20nMAssay Description:Inhibition of [14C]arachidonic acid conversion to 5-HETE by broken cell 5-lipoxygenase in vitro (guinea pig PMN)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50012827(10H-Phenoxazine | CHEMBL276850 | PHENOXAZINE)
Affinity DataIC50: 320nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012827(10H-Phenoxazine | CHEMBL276850 | PHENOXAZINE)
Affinity DataIC50: 350nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Westphalian Wilhelms-University

Curated by ChEMBL
LigandPNGBDBM50012827(10H-Phenoxazine | CHEMBL276850 | PHENOXAZINE)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of pig tubulin polymerization determined after 45 mins at 37 degC by turbidimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed