BDBM50101828 7-[(1R,2R,3R)-3-Hydroxy-2-((E)-(R)-3-hydroxy-oct-1-enyl)-5-oxo-cyclopentyl]-heptanoic acid::CHEMBL62570::PGE1::US9180116, PGE1

SMILES CCCCC[C@@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O

InChI Key InChIKey=GMVPRGQOIOIIMI-UHFFFAOYSA-N

Data  12 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50101828   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Cayman Chemical

US Patent
LigandPNGBDBM50101828(CHEMBL62570 | PGE1 | 7-[(1R,2R,3R)-3-Hydroxy-2-((E...)
Affinity DataEC50:  0.220nMT: 2°CAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Cayman Chemical

US Patent
LigandPNGBDBM50101828(CHEMBL62570 | PGE1 | 7-[(1R,2R,3R)-3-Hydroxy-2-((E...)
Affinity DataEC50:  16.5nMT: 2°CAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 ul of reduced serum medium containing 0.5% FBS. Place the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Kyoto University

Curated by PDSP Ki Database
LigandPNGBDBM50101828(CHEMBL62570 | PGE1 | 7-[(1R,2R,3R)-3-Hydroxy-2-((E...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Bovine)
Alcon Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50101828(CHEMBL62570 | PGE1 | 7-[(1R,2R,3R)-3-Hydroxy-2-((E...)
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Mouse)
Kyoto University

Curated by PDSP Ki Database
LigandPNGBDBM50101828(CHEMBL62570 | PGE1 | 7-[(1R,2R,3R)-3-Hydroxy-2-((E...)
Affinity DataKi:  2.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Bovine)
Alcon Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50101828(CHEMBL62570 | PGE1 | 7-[(1R,2R,3R)-3-Hydroxy-2-((E...)
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Mouse)
Kyoto University

Curated by PDSP Ki Database
LigandPNGBDBM50101828(CHEMBL62570 | PGE1 | 7-[(1R,2R,3R)-3-Hydroxy-2-((E...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
TargetProstacyclin receptor(Mouse)
Kyoto University

Curated by PDSP Ki Database
LigandPNGBDBM50101828(CHEMBL62570 | PGE1 | 7-[(1R,2R,3R)-3-Hydroxy-2-((E...)
Affinity DataKi:  33nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Mouse)
Kyoto University

Curated by PDSP Ki Database
LigandPNGBDBM50101828(CHEMBL62570 | PGE1 | 7-[(1R,2R,3R)-3-Hydroxy-2-((E...)
Affinity DataKi:  36nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Royal Postgraduate Medical School

Curated by PDSP Ki Database
LigandPNGBDBM50101828(CHEMBL62570 | PGE1 | 7-[(1R,2R,3R)-3-Hydroxy-2-((E...)
Affinity DataKi:  137nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2011
Entry Details Article
PubMed
TargetProstacyclin receptor(Mouse)
Kyoto University

Curated by PDSP Ki Database
LigandPNGBDBM50101828(CHEMBL62570 | PGE1 | 7-[(1R,2R,3R)-3-Hydroxy-2-((E...)
Affinity DataKi:  137nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Rat)
Kyoto University

Curated by PDSP Ki Database
LigandPNGBDBM50101828(CHEMBL62570 | PGE1 | 7-[(1R,2R,3R)-3-Hydroxy-2-((E...)
Affinity DataKi:  3.76E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
TargetThromboxane A2 receptor(Mouse)
University of Edinburgh

Curated by PDSP Ki Database
LigandPNGBDBM50101828(CHEMBL62570 | PGE1 | 7-[(1R,2R,3R)-3-Hydroxy-2-((E...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Bovine)
Alcon Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50101828(CHEMBL62570 | PGE1 | 7-[(1R,2R,3R)-3-Hydroxy-2-((E...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed