BDBM50470108 AGN 204332::Ingenol Mebutate::PEP-005::PEP005::Picato

SMILES C/C=C(/C)\C(=O)O[C@H]1C(=C[C@@]23[C@@]1([C@@H](C(=C[C@H](C2=O)[C@H]4[C@H](C4(C)C)C[C@H]3C)CO)O)O)C

InChI Key InChIKey=VDJHFHXMUKFKET-UHFFFAOYSA-N

Data  3 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50470108   

LigandPNGBDBM50470108(AGN 204332 | Ingenol Mebutate | PEP-005 | PEP005 |...)
Affinity DataEC50:  73nMAssay Description:Activation of PKC in human platelet assessed as induction of platelet aggregation measured within 15 mins by tribidimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50470108(AGN 204332 | Ingenol Mebutate | PEP-005 | PEP005 |...)
Affinity DataEC50:  4.10nMAssay Description:Activation of PKCdelta (unknown origin) after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50470108(AGN 204332 | Ingenol Mebutate | PEP-005 | PEP005 |...)
Affinity DataEC50:  4.10nMAssay Description:Activation of PKCdelta (unknown origin) using phosphatidylserine as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed