BDBM50073727 (S)-3-[(S)-2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-yl)-2-methyl-propionylamino]-4-phenyl-butyric acid::CHEMBL145133::PD-140547

SMILES C[C@@](Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)N[C@H](CC(O)=O)Cc1ccccc1

InChI Key

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50073727   

TargetGastrin/cholecystokinin type B receptor(Mouse)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50073727((S)-3-[(S)-2-(Adamantan-2-yloxycarbonylamino)-3-(1...)
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]propionyl-CCK-8 binding to mouse cerebral cortex membrane cholecystokinin-B (CCK-B) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50073727((S)-3-[(S)-2-(Adamantan-2-yloxycarbonylamino)-3-(1...)
Affinity DataIC50: 539nMAssay Description:Inhibition of [3H]propionyl-CCK-8 binding to rat pancreas cholecystokinin-A (CCK-A) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Mouse)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50073727((S)-3-[(S)-2-(Adamantan-2-yloxycarbonylamino)-3-(1...)
Affinity DataIC50: 13nMAssay Description:Inhibition of [125I]CCK-8 to Cholecystokinin type B receptor in the mouse cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50073727((S)-3-[(S)-2-(Adamantan-2-yloxycarbonylamino)-3-(1...)
Affinity DataIC50: 539nMAssay Description:Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGastrin/cholecystokinin type B receptor(Mouse)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50073727((S)-3-[(S)-2-(Adamantan-2-yloxycarbonylamino)-3-(1...)
Affinity DataKi:  13nMAssay Description:Cholecystokinin type B receptor binding assay performed on homogenized cerebral cortex from male mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2019
Entry Details Article
PubMed