BDBM50055724 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyridin-2-yl-piperazine::CHEMBL418937::PD-137789

SMILES C(CN1CCN(CC1)c1ccccn1)[C@H]1CCC(=CC1)c1ccccc1

InChI Key InChIKey=MQHGACGPMGUHSJ-UHFFFAOYSA-N

Data  1 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50055724   

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50055724(PD-137789 | 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-et...)
Affinity DataIC50: 412nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(1A) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50055724(PD-137789 | 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-et...)
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro antagonist binding affinity was determined by displacing the [3H]-SCH- in rat striatal Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(1A) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50055724(PD-137789 | 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-et...)
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro antagonist binding affinity was determined by displacing the [3H]-SCH- in rat striatal Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50055724(PD-137789 | 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-et...)
Affinity DataIC50: 412nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50055724(PD-137789 | 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-et...)
Affinity DataIC50: 88nMAssay Description:In vitro agonist binding affinity was determined by displacing the [3H]N-propylnorapomorphine ([3H]NPA) in rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50055724(PD-137789 | 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-et...)
Affinity DataIC50: 704nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50055724(PD-137789 | 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-et...)
Affinity DataIC50: 82nMAssay Description:In vitro agonist binding affinity was determined by displacing the [3H]N-propylnorapomorphine ([3H]NPA) in rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50055724(PD-137789 | 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-et...)
Affinity DataKi:  412nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed