BDBM50010359 (S)-5-Diphenylacetyl-1-(4-methoxy-3-methyl-benzyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid::5-Diphenylacetyl-1-(4-methoxy-3-methyl-benzyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid::5-diphenylcarbamoyl-1-(4-methoxy-2-methylbenzyl)-(6S)-4,5,6,7-tetrahydro-1H-imidazo[5,4-c]pyridine-6-carboxylic acid::CHEMBL294558::PD-121981

SMILES COc1ccc(Cn2cnc3CN([C@@H](Cc23)C(O)=O)C(=O)C(c2ccccc2)c2ccccc2)cc1C

InChI Key InChIKey=QEKGGRXXFXFZAV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50010359   

TargetType-2 angiotensin II receptor(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50010359(CHEMBL294558 | PD-121981 | 5-diphenylcarbamoyl-1-(...)
Affinity DataIC50: 10nMAssay Description:Binding affinity towards angiotensin II AT2 receptor subtype was determined using rat isolated adrenal cortical microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-2 angiotensin II receptor(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50010359(CHEMBL294558 | PD-121981 | 5-diphenylcarbamoyl-1-(...)
Affinity DataIC50: 38nMAssay Description:Compound was evaluated for inhibition of Angiotensin II receptor, type 2 in rat midbrain AT2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50010359(CHEMBL294558 | PD-121981 | 5-diphenylcarbamoyl-1-(...)
Affinity DataIC50: 70nMAssay Description:Inhibitory activity at Angiotensin II type 2 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
LigandPNGBDBM50010359(CHEMBL294558 | PD-121981 | 5-diphenylcarbamoyl-1-(...)
Affinity DataIC50: 70nMAssay Description:Binding affinity against Angiotensin II receptor, from rat adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2019
Entry Details Article
PubMed