BDBM50209223 CHEBI:28741::Dentiplus::Duraphat::En-De-Kay::Fluor Ret::Fluor-A-Day::Fluorigard::Fluorigard Daily::Fluorigard Weekly::Fluorinse::Minute-Gel::NaFril Ret::Neutra Care::Ossin::Osteofluor::Pediaflor::Point-Two::Sodium Fluoride::Zymafluor

SMILES [Na+]

InChI Key InChIKey=FKNQFGJONOIPTF-UHFFFAOYSA-N

Data  7 KI

PDB links: 12021 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50209223   

TargetCarbonic anhydrase(Methanosarcina thermophila)
Italy

Curated by ChEMBL
LigandPNGBDBM50209223(Dentiplus | Duraphat | CHEBI:28741 | En-De-Kay | F...)
Affinity DataKi: >2.00E+8nMAssay Description:Inhibition of Methanosarcina thermophila recombinant carbonic anhydrase gamma assessed as inhibition of CO2 hydration preincubated for 15 mins by Lin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2018
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Italy

Curated by ChEMBL
LigandPNGBDBM50209223(Dentiplus | Duraphat | CHEBI:28741 | En-De-Kay | F...)
Affinity DataKi: >3.00E+8nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 assessed as inhibition of CO2 hydration preincubated for 15 mins by Lineweaver-burk plot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Italy

Curated by ChEMBL
LigandPNGBDBM50209223(Dentiplus | Duraphat | CHEBI:28741 | En-De-Kay | F...)
Affinity DataKi: >3.00E+8nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 assessed as inhibition of CO2 hydration incubated for 15 mins prior to testing by stopped flow C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Italy

Curated by ChEMBL
LigandPNGBDBM50209223(Dentiplus | Duraphat | CHEBI:28741 | En-De-Kay | F...)
Affinity DataKi: >3.00E+8nMAssay Description:Inhibition of human CA2 incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Italy

Curated by ChEMBL
LigandPNGBDBM50209223(Dentiplus | Duraphat | CHEBI:28741 | En-De-Kay | F...)
Affinity DataKi: >3.00E+8nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Italy

Curated by ChEMBL
LigandPNGBDBM50209223(Dentiplus | Duraphat | CHEBI:28741 | En-De-Kay | F...)
Affinity DataKi: >3.00E+8nMAssay Description:Inhibition of human carbonic anhydrase-2 at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50209223(Dentiplus | Duraphat | CHEBI:28741 | En-De-Kay | F...)
Affinity DataKi: >3.00E+8nMAssay Description:Inhibition of human carbonic anhydrase-1 at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)