BDBM50057482 4-(2-{4-[(S)-1-(4-Isobutyl-phenyl)-ethoxy]-2,3-dimethyl-benzoylamino}-phenoxy)-butyric acid::4-(2-{4-[1-(4-Isobutyl-phenyl)-ethoxy]-2,3-dimethyl-benzoylamino}-phenoxy)-butyric acid::CHEMBL24470::ONO-3805

SMILES CC(C)Cc1ccc(cc1)[C@H](C)Oc1ccc(C(=O)Nc2ccccc2OCCCC(O)=O)c(C)c1C

InChI Key InChIKey=XWNSOVPLENXWNU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057482   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50057482(ONO-3805 | 4-(2-{4-[(S)-1-(4-Isobutyl-phenyl)-etho...)
Affinity DataIC50: 256nMAssay Description:Inhibition of human 5-alpha reductase 2 isozyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50057482(ONO-3805 | 4-(2-{4-[(S)-1-(4-Isobutyl-phenyl)-etho...)
Affinity DataIC50: 180nMAssay Description:Compound was tested in vitro for inhibitory activity against type 1 5-alpha reductase Isozyme homogenated from rat epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Zeria Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057482(ONO-3805 | 4-(2-{4-[(S)-1-(4-Isobutyl-phenyl)-etho...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of Steroid 5-alpha-reductase from Dawley rat prostateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2018
Entry Details Article
PubMed